What should be monitored during the administration of large doses of local anesthetics?

Monitoring the patient's vital signs and signs of CNS or cardiovascular toxicity during the administration of large doses of local anesthetics is crucial due to the inherent risks associated with these agents. Local anesthetics can have systemic effects if administered in excessive amounts, leading to adverse reactions.

Changes in vital signs such as heart rate, blood pressure, and respiratory rate can indicate the onset of toxicity. Central nervous system toxicity may present as symptoms ranging from mild (e.g., tinnitus, dizziness) to severe (e.g., seizures, loss of consciousness). Cardiovascular effects may lead to arrhythmias or hypotension, which can be life-threatening. Therefore, by continuously assessing these parameters, healthcare providers can promptly identify and manage any adverse effects, ensuring patient safety throughout the procedure. Monitoring these signs allows for timely interventions if signs of toxicity arise, preventing complications associated with large doses of local anesthetics.